This week, Fluorobiotech’s COO, Ross Rayne Vermeulen, attended a landmark event in Johannesburg celebrating the launch of clinical trials for South Africa’s first domestically developed cholera vaccine, a major achievement led by Biovac. The ceremony marked the start of Phase I safety trials, representing a pivotal advancement not only for South African science, but for the entire African vaccine ecosystem.
A Major Step Toward Regional Health Security
As emphasized by South Africa’s Minister of Health, Dr. Aaron Motsoaledi, the development of a locally designed and manufactured cholera vaccine underscores Africa’s growing capacity to reduce its reliance on global supply chains. The COVID-19 pandemic highlighted the vulnerabilities inherent in depending on external suppliers for life-saving vaccines and biologics. This new milestone demonstrates that African institutions are rapidly building the technical and manufacturing capabilities needed to respond to public health challenges with homegrown solutions.
Biovac’s oral cholera vaccine arrives at a critical time. Cholera outbreaks continue to affect communities across the continent, placing thousands at risk each year. With global shortages of cholera vaccines affecting response efforts worldwide, South Africa’s entry into vaccine development and production represents a timely and strategically important contribution to global health.
A Reflection of Africa’s Scientific Excellence
The successful advancement of this vaccine candidate into human trials is a testament to the vision and leadership of Dr. Morena Makhoana, CEO of Biovac, and the dedication of the entire Biovac team. It reflects years of investment in local R&D capacity, workforce development, and regulatory readiness – pillars that form the foundation of a truly resilient vaccine manufacturing ecosystem.
For Africa, this achievement sends a clear message: the continent is steadily moving from being primarily a consumer of vaccines to becoming an active contributor to global vaccine innovation and supply.
Fluorobiotech’s Commitment to Regional Biomanufacturing
At Fluorobiotech, we are inspired by Biovac’s progress and proud to contribute to the broader momentum taking shape within Africa’s vaccine and biologics manufacturing landscape. Strengthening local production is central to achieving health sovereignty, the ability of African nations to develop, produce, and distribute essential medical countermeasures independently and sustainably.
Our work in enabling enzyme production, mRNA manufacturing support, and capacity building aligns strongly with this vision. As more African-led vaccine initiatives move toward clinical development and scale-up, regional collaboration will remain essential for ensuring long-term success.
A Milestone Worth Celebrating
We extend our warmest congratulations to Dr. Makhoana and the entire Biovac team on this remarkable accomplishment. Their work exemplifies what is possible when scientific excellence, committed partnerships, and public health priorities come together.
This is a historic moment for South African science and a promising step toward a future where Africa plays a central role in developing the vaccines and biologics that safeguard the health of its people.

