HIV-2 gp36 (Ectodomain)

Recombinant HIV-2 gp36 (Ectodomain) is a high-purity envelope glycoprotein widely used for the specific detection of antibodies against HIV-2 infection. As the functional and structural equivalent of HIV-1 gp41, gp36 mediates membrane fusion during viral entry while containing immunodominant epitopes that enable reliable serological differentiation between HIV-1 and HIV-2 due to their limited cross-reactivity. Recombinant gp36 is an essential antigen for differential HIV immunoassays, confirmatory testing, and multiplex diagnostic platforms, supporting accurate species discrimination and comprehensive HIV diagnostic coverage. Its inclusion is particularly valuable for assays intended for global deployment, including regions where HIV-2 remains endemic in West Africa.

‍